Select your region or country.
特点：1700 nm 的优势 | 超连续谱光源
The L15077-C7 supercontinuum light source is a compact laser light source that emits broadband near-infrared laser light generated from nonlinear optical phenomenon induced by an ultrashort pulsed laser.
It provides the high directivity and high brightness of a laser along with the broad spectrum of a lamp light source. Compared to other company supercontinuum light sources the L15077-C7 delivers a light output with greater stability to give accurate measurements, analyses and inspections over a diverse range of applications.
1700 nm 的优势
滨松的超连续谱光源拥有主要位于 1700 nm 波段的宽频段。因此，它适用于使用第 3 光学窗口 (1600 - 1800 nm) 对生物样品进行 OCT（光学相干断层扫描）测量，并能够对高度分散的生物组织进行高分辨率深度成像。
一般来说，生物组织成像选择一个称为光学窗口的波长带，水和血红蛋白[1]对该波长带的吸收较弱。具体而言，按照水的吸收逐级减少的波长带分别称为第 1 光学窗口 (800 - 900 nm)、第 2 光学窗口 (1100 - 1300 nm) 和第 3 光学窗口 (1600 - 1800 nm)。其中，第 3 光学窗口最适合用于深度成像，因为它受生物组织光散射的影响较小。
如下图所示，在第 1 和第 2 光学窗口（0.8 μm、1.1 μm、1.3 μm）中，穿透深度随着生物组织散射的增加而减小（脂质%），但在第 3 光学窗口 (1.7 μm) 中，即使散射增加，穿透深度也保持不变[2]。
生物组织光吸收和光散射的波长特性 [1]
在每个波长带的穿透深度 [2]
此外，当应用于 SD-OCT（光谱域-光学相干断层扫描）时，确认在 1300 nm 波段，信噪比随着穿透深度的增加而降低，但在 1700 nm 波段，即便穿透深度增加[3]，信噪比仍保持不变。
测量系统
信噪比
由名古屋大学研究生院电气工程系西泽研究实验室提供
高轴向分辨率
确定 OCT 中的轴向分辨率 (ΔZ) 的一个因素是光源的半宽度 (Δλ) 。确定轴向分辨率的公式如下。
由于半宽度 (Δλ) 受倒数影响，因此高分辨率测量需要宽的半宽度。此外，与通常用于 OCT 的 1300 nm 或更低波段的光源相比，当使用 1700 nm 波段的光源进行深度成像时，半宽度 (Δλ) 必需更宽，因为中心波长 (λ0) 的平方值会影响轴向分辨率[4]。
滨松的超连续谱光源的半宽度 (Δλ) 超过 ±300 nm，中心位于 1700 nm 波段。这即使在深度成像中也能实现高轴向分辨率。
1700 nm 中心波长的轴向分辨率
由名古屋大学研究生院电气工程系西泽研究实验室提供
低噪声水平
滨松的超连续谱光源配备了与名古屋大学西泽实验室合作开发的独特且高度稳定的超连续谱发光系统。与其他公司制造的超连续谱光源相比，噪声特性约为 1/10，可实现高灵敏度测量[5][6]。
过剩噪声
OCT 系统的噪声模型 [7]
由 Jun Zhu 和 Vivek J. Srinivasan（加州大学戴维斯分校）提供
参考资料
|
|
|
|
|
|---|---|---|---|
|
|
M. S. Patterson 等人。 | 光学辐射在组织中的传播。2：组织的光学特性及相应的通量分布 | Lasers in Medical Science，第 6 卷，第 379 - 390 页 (1991) |
|
|
N.Nishizawa、H.Kawagoe、M.Yamanaka、M.Matsushima、K.Mori、T.Kawabe | 使用超连续谱进行生物医学成像的超高分辨率光学相干断层扫描的波长依赖性 | IEEE 量子电子学精选主题期刊，第 25 卷，编号 1，2019 年 1 月/2 月 |
|
|
M.Yamanaka、N.Hayakawa、N.Nishizawa | 在 1700 nm 光谱带通过光学相干显微镜进行深度组织成像的信号背景比和横向分辨率 | 科学报告第 9 卷，文章编号：16041 (2019) |
|
|
S. Ishida 和 N. Nishizawa | 800 - 1700nm 波长范围超高分辨率光学相干断层扫描图像对比及成像深度的定量比较 | Biomed. 光学 Express，第 3 卷，第 282 页, 2012。 |
|
|
Jun Zhu 和 Vivek J. Srinivasan | 使用 1700 nm 光学相干显微镜法透过磨薄颅骨进行活体小鼠脑成像（会议报告） | 国际光电工程学会 会议记录 11228，生物医学中的光学相干断层扫描和相干域光学方法 XXIV ，112280P（2020 年 3 月 9 日） |
|
|
Jun Zhu、Hercules Rezende Freitas、Izumi Maezawa、Lee-way Jin、Vivek J. Srinivasan | 1700 nm 光学相干显微镜可在活体小鼠脑内进行微创、无标记、深度光学活检 | 光：科学与应用第 10 卷，文章编号：145 (2021) |
|
|
Shau Poh Chong、Marcel Bernucci、Harsha Radhakrishnan、Vivek J. Srinivasan | 使用基于纤维的可见光 OCT 检眼镜进行结构和功能性人眼视网膜成像 | Biomed. 光学 Express，第 8 卷，第 1 期，第 323-337 页，2017 |
- Confirmation
-
It looks like you're in the . If this is not your location, please select the correct region or country below.
You're headed to Hamamatsu Photonics website for (Chinese). If you want to view an other country's site, the optimized information will be provided by selecting options below.
In order to use this website comfortably, we use cookies. For cookie details please see our cookie policy.
- Cookie Policy
-
This website or its third-party tools use cookies, which are necessary to its functioning and required to achieve the purposes illustrated in this cookie policy. By closing the cookie warning banner, scrolling the page, clicking a link or continuing to browse otherwise, you agree to the use of cookies.
Hamamatsu uses cookies in order to enhance your experience on our website and ensure that our website functions.
You can visit this page at any time to learn more about cookies, get the most up to date information on how we use cookies and manage your cookie settings. We will not use cookies for any purpose other than the ones stated, but please note that we reserve the right to update our cookies.
1. What are cookies?
For modern websites to work according to visitor’s expectations, they need to collect certain basic information about visitors. To do this, a site will create small text files which are placed on visitor’s devices (computer or mobile) - these files are known as cookies when you access a website. Cookies are used in order to make websites function and work efficiently. Cookies are uniquely assigned to each visitor and can only be read by a web server in the domain that issued the cookie to the visitor. Cookies cannot be used to run programs or deliver viruses to a visitor’s device.
Cookies do various jobs which make the visitor’s experience of the internet much smoother and more interactive. For instance, cookies are used to remember the visitor’s preferences on sites they visit often, to remember language preference and to help navigate between pages more efficiently. Much, though not all, of the data collected is anonymous, though some of it is designed to detect browsing patterns and approximate geographical location to improve the visitor experience.
Certain type of cookies may require the data subject’s consent before storing them on the computer.
2. What are the different types of cookies?
This website uses two types of cookies:
- First party cookies. For our website, the first party cookies are controlled and maintained by Hamamatsu. No other parties have access to these cookies.
- Third party cookies. These cookies are implemented by organizations outside Hamamatsu. We do not have access to the data in these cookies, but we use these cookies to improve the overall website experience.
3. How do we use cookies?
This website uses cookies for following purposes:
- Certain cookies are necessary for our website to function. These are strictly necessary cookies and are required to enable website access, support navigation or provide relevant content. These cookies direct you to the correct region or country, and support security and ecommerce. Strictly necessary cookies also enforce your privacy preferences. Without these strictly necessary cookies, much of our website will not function.
- Analytics cookies are used to track website usage. This data enables us to improve our website usability, performance and website administration. In our analytics cookies, we do not store any personal identifying information.
- Functionality cookies. These are used to recognize you when you return to our website. This enables us to personalize our content for you, greet you by name and remember your preferences (for example, your choice of language or region).
- These cookies record your visit to our website, the pages you have visited and the links you have followed. We will use this information to make our website and the advertising displayed on it more relevant to your interests. We may also share this information with third parties for this purpose.
Cookies help us help you. Through the use of cookies, we learn what is important to our visitors and we develop and enhance website content and functionality to support your experience. Much of our website can be accessed if cookies are disabled, however certain website functions may not work. And, we believe your current and future visits will be enhanced if cookies are enabled.
4. Which cookies do we use?
There are two ways to manage cookie preferences.
- You can set your cookie preferences on your device or in your browser.
- You can set your cookie preferences at the website level.
If you don’t want to receive cookies, you can modify your browser so that it notifies you when cookies are sent to it or you can refuse cookies altogether. You can also delete cookies that have already been set.
If you wish to restrict or block web browser cookies which are set on your device then you can do this through your browser settings; the Help function within your browser should tell you how. Alternatively, you may wish to visit www.aboutcookies.org, which contains comprehensive information on how to do this on a wide variety of desktop browsers.
5. What are Internet tags and how do we use them with cookies?
Occasionally, we may use internet tags (also known as action tags, single-pixel GIFs, clear GIFs, invisible GIFs and 1-by-1 GIFs) at this site and may deploy these tags/cookies through a third-party advertising partner or a web analytical service partner which may be located and store the respective information (including your IP-address) in a foreign country. These tags/cookies are placed on both online advertisements that bring users to this site and on different pages of this site. We use this technology to measure the visitors' responses to our sites and the effectiveness of our advertising campaigns (including how many times a page is opened and which information is consulted) as well as to evaluate your use of this website. The third-party partner or the web analytical service partner may be able to collect data about visitors to our and other sites because of these internet tags/cookies, may compose reports regarding the website’s activity for us and may provide further services which are related to the use of the website and the internet. They may provide such information to other parties if there is a legal requirement that they do so, or if they hire the other parties to process information on their behalf.
If you would like more information about web tags and cookies associated with on-line advertising or to opt-out of third-party collection of this information, please visit the Network Advertising Initiative website http://www.networkadvertising.org.
6. Analytics and Advertisement Cookies
We use third-party cookies (such as Google Analytics) to track visitors on our website, to get reports about how visitors use the website and to inform, optimize and serve ads based on someone's past visits to our website.
You may opt-out of Google Analytics cookies by the websites provided by Google:
https://tools.google.com/dlpage/gaoptout?hl=en
As provided in this Privacy Policy (Article 5), you can learn more about opt-out cookies by the website provided by Network Advertising Initiative:
http://www.networkadvertising.org
We inform you that in such case you will not be able to wholly use all functions of our website.
Close