滨松工程师提供许多不同的技术来满足客户的需求。请告诉我们您的需求。
可通过使用荧光染料测量细胞内钙的增加来监测 G(q) 蛋白偶联受体的激活。荧光动力学读板机和液体处理技术的最新进展,使得在高通量筛选 (HTS) 中以 1536 孔板形式追踪细胞内钙的这些瞬时变化成为可能。在这里,我们应用最新一代荧光动力学读板机对 G 蛋白偶联受体 (GPCR) 的激动剂和拮抗剂进行多重筛选。这种多重测定形式为 G(q) 偶联 GPCR 靶标的 HTS 提供了一种高效而又划算的方法。
检测药物开发技术。2010 年 6 月;8(3):367-79。doi:10.1089/adt.2009.0245。
作者 | 标题 | 来源 |
---|---|---|
Ke Liu、Noel Southall、Steve A. Titus、James Inglese、Robert L. Eskay、Paul Shinn、Christopher P. Austin、Markus A. Heilig、Wei Zheng | 用于鉴定 GPCR 激动剂和拮抗剂的多重钙含量测定 | 测定药物开发技术。2010 年 6 月;8(3):367-79 |
应用 说明第 | 标题 |
---|---|
FDSS 应用说明第 15 | FDSS 用途说明 15,使用 FDSS6000 将细胞暴露于用户定义的波长和持续时间的单脉冲光中 [0.1MB/PDF] |
年份 | 标题 |
---|---|
ROS | |
2015 | 基于 Pholasin® 的 ABEL® 检测,用于测量 FDSS 平台上实时产生的 ROS |
2015 | TNF-α 引发的原代人嗜中性粒细胞中 ROS 释放的小分子调节 |
癫痫 | |
2014 | 适用于 MTS 的急性癫痫体外模型 |
孔分析 | |
2015 | 光遗传学:电压门控离子通道的美好未来 |
2014 | 光遗传学:电压门控离子通道的美好未来 |
光遗传学 | |
2015 | 使用基于成像的酶标仪分析基于细胞的荧光测定数据的新方法 |
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