该技术是高精度观察生物样本深部区域的理想选择,将成为了解大脑功能不可或缺的工具。 这是通过使用我们的空间光调制器 (SLM) (*1) 和我们多年来培育的独有光学控制技术进行密集研究得以实现的。
应用这项研究的结果将轻松提高配备 SLM 的双光子激发显微镜的分辨率。这种新的显微镜技术正在神经科学和生物学等广泛领域中得到切实应用。它允许对生物样本中的深部区域进行详细测量,并对组成细胞的细胞器状态的变化进行高度精准的观察。因此,它在研究大脑功能、肾脏疾病和其他疾病的用途中成为前景光明的工具。
这项研究成果于 4 月 20 日发表于神经科学领域的重要期刊《神经科学前沿》(Frontiers in Neuroscience)。上述成果是同滨松医科大学的生物光子学创新研究实验室和病毒与寄生虫学研究课程项目合作达成的。
*1:空间光调制器(即 SLM)是一种利用液晶控制入射光波前(例如激光器的波前)以调整反射光波前形状的光学装置。使用空间光调制器可以自由地控制激光光束形状,例如用于分化入射光并校正光束变形。
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