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NanoZoomer® S60v2 数字切片扫描仪
C16600-01
该型号同时支持明场成像和荧光成像。该设备专为使用巨型载玻片而设计，可实现大型组织样本的虚拟化。这有助于实现病理组织观测的数字化，从而加强研究与药物发现应用。
NanoZoomer 是滨松集团（欧盟、日本、英国、美国）的注册商标。
荧光扫描的特殊功能
除了专有高灵敏度相机之外，我们还采用了带有滤光片切换机制的落射照明光学系统，可实现多达 6 个通道的多荧光扫描。每个通道均可输出图像文件，允许单波长查看或叠加多个波长进行综合分析。
示例：多重荧光染色小鼠标本（6 通道）“图像 1”
●扫描速度（20 倍模式）：约 16 分钟
● 扫描区域：7 mm × 12 mm
● 荧光染料：DAPI / 水绿色 / 绿色 / 金色 / 红色 / 远红
● 曝光时间：80 ms / 32 ms / 112 ms / 224 ms / 224 ms / 112 ms
● 缩放比例：各 8 倍
图像 1
功能
缩放功能
通过在扫描过程中对荧光强度值进行缩放处理，可在更短的曝光时间内获得明亮的荧光图像。曝光时间可缩短至原时长的 1/8，从而加快扫描速度并降低荧光褪色的风险。
扫描区域（40 倍模式）：10 mm × 10 mm
荧光滤波器：用于 DAPI / FITC / TRITC
* 扫描时间以实际测量为准，包括从载玻片加载到扫描完成的整个过程。
图像 2
示例：小鼠肾脏荧光标本“图像 2”
● 扫描速度（40 倍模式）：约 9 分钟
● 扫描区域：7 mm × 13 mm（图像为局部视场）
● 荧光染料：DAPI / Alexa 488 / Alexa 568
● 曝光时间：10 ms / 5 ms / 5 ms
焦点偏移功能
如图像 3 所示，焦点偏移功能可以精准调整每个波长对应的焦平面。通过为每个染色物体设置焦点偏移值，可以在所有波长获取具有准确焦点的清晰图像。
图像 3
多载玻片扫描能力
- 最多 60 片标准载玻片
- 最多 30 片巨型载玻片
高速扫描*（明场）
- 20 倍模式：60 秒/张
- 40 倍模式：75 秒/张
*扫描时间基于具有 5 个焦点的 15 mm × 15 mm 区域。
特殊站点
全视野切片成像特殊站点是适合研究和病理学的全视野切片成像功能部分。
详细参数
| 产品名称 | NanoZoomerⓇ S60v2 数字切片扫描仪 | |
|---|---|---|
| 产品编号 | C16600-01 | |
| 扫描速度 *1 | 20 倍模式 | 约 60 s (15 mm x 15 mm) |
| 40 倍模式 | 约 75 s (15 mm x 15 mm) | |
| 物镜 | 20× NA 0.75（用户可以在扫描开始时选择 20 倍或 40 倍模式） | |
| 兼容的载玻片 *2 | 标准载玻片 | 25.0 mm 至 26.0 mm × 75.0 mm 至 76.0 mm（厚度为 0.9mm 至 1.2mm） |
| 巨型载玻片（选配） | 51.0 mm 至 52.0 mm × 75.0 mm 至 76.0 mm（厚度为 0.9mm 至 1.2mm） | |
| 玻片装载器 | 标准载玻片 | 最多 60 片（20 片 × 3 盒）*3 |
| 巨型载玻片 | 最多 30 片（10 片 × 3盒）*3 | |
| 扫描分辨率 | 20 倍模式 | 约 0.46 μm/像素 |
| 40 倍模式 | 约 0.23 μm/像素 | |
| 聚焦法 | 预聚焦图 | |
| Z-stack 功能 | 包含（最多 99 层，间距 0.1μm 或以上） | |
| 图像压缩 | 压缩图像 (JPEG)、未压缩图像（8 位） | |
| 可读条形码 | 一维条形码 | Code 39 码 、Code 128 码 、交叉 25 码、Codabar 码、EAN-8 码和 UPC-E 码 |
| 二维条形码 *4 | DataMatrix 码 (ECC200)、QR 码 Ⓡ（QR 码 Model-1、QR 码 Model-2） | |
| 电源 | AC 100 V 至交流 240 V | |
| 用电功耗（仅限扫描仪） | 约 120 VA | |
*1 扫描具有 5 个焦点的 15 mm × 15 mm 正方形区域时。
*2 标准载玻片是单玻片，巨型载玻片是双倍宽度的大型玻片。
*3 最多可设置 3 个玻片盒，支持标准和巨型载玻片的组合使用。
*4 读取二维条码需安装选配软件。
尺寸
重要声明
矩阵表显示了在每个地区注册为医疗系统的 NanoZoomer IVD 系列。
| 美国 | 欧盟/欧洲经济区 | 英国 | 瑞士 | 中国 | 加拿大 | 台湾 | 韩国 | 日本 | 土耳其 | 以色列 | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NanoZoomer S20MD | C16300-21MDEU | C16300-21MDEU | C16300-21MDEU | C16300-31MDCA | C16300-61MDK | C16300-11MDJ | C16300-21MDEU | ||||
| NanoZoomer S60v2MD | C16600-21MDEU | C16600-21MDEU | C16600-21MDEU | C16600-21MDEU | C16600-21MDEU | ||||||
| NanoZoomer S360MD | C13220-01MD | C13220-21MDEU | C13220-21MDEU | C13220-21MDEU | C13220-61MDK | C13220-11MDJ | C13220-21MDEU | C13220-21MDEU | |||
| NanoZoomer S540MD | C17400-21MDEU | C17400-21MDEU | C17400-21MDEU | C17400-21MDEU | C17400-21MDEU | ||||||
| NanoZoomer S60 | C13210-01 | ||||||||||
| NanoZoomer S360 | C13220-01 | C13220-31 | C13220-01 | ||||||||
| NanoZoomer S210 | C13239-01 | ||||||||||
| NanoZoomer-SQ | C13140-01 |
重要声明
在美国，C13220-01MD NanoZoomer S360MD 玻片扫描仪系统可用于以下经验证的 FDA 批准显示器，进行初步诊断：
・JVC JD-C240BN01A *显示器经 FDA 批准可与 NanoZoomer S360MD 配合使用。
・BARCO MDPC-8127 *显示器本身已获得 FDA 批准。
在欧洲，以下产品符合体外诊断用途的 IVDR (EU)、UK MDR2002 (UK) 和 IvDO (CH) 标准：
C13220-21MDEU NanoZoomer S360MD 玻片扫描仪系统、C16600-21MDEU NanoZoomer S60v2MD 玻片扫描仪系统、C16300-21MDEU NanoZoomer S20MD 玻片扫描仪系统和 C17400-21MDEU NanoZoomer S540MD 玻片扫描仪系统。
在中国，以下产品已注册用于体外诊断：
C13220-01 NanoZoomer S360、C13239-01 NanoZoomer S210、C13210-01 NanoZoomer S60 和 C13140-01 NanoZoomer-SQ。
在加拿大，C13220-31 NanoZoomer S360 和 C16300-31MDCA NanoZoomer S20MD 玻片扫描仪系统具有医疗器械许可证。
在中国台湾，C13220-01 NanoZoomer S360 已注册为医疗器械。
在韩国，C13220-61MDK NanoZoomer S360MD 和 C16300-61MDK NanoZoomer S20MD 玻片扫描仪系统已注册为体外诊断医疗设备。
在日本，C13220-11MDJ NanoZoomer S360MD 玻片扫描仪系统和 C16300-11MDJ NanoZoomer S20MD 玻片扫描仪系统已获批准为医疗器械。
在土耳其，C13220-21MDEU NanoZoomer S360MD 玻片扫描仪系统、C16600-21MDEU NanoZoomer S60v2MD 玻片扫描仪系统和 C16300-21MDEU NanoZoomer S20MD 玻片扫描仪系统已注册为医疗器械。
在以色列，C13220-21MDEU NanoZoomer S360MD 玻片扫描仪系统和 C16600-21MDEU NanoZoomer S60v2MD 玻片扫描仪系统已注册为医疗器械。
在其他国家/地区，NanoZoomer 系列仅供研究使用，不得用于临床诊断目的。
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