NanoZoomer® S60v2 数字切片扫描仪
具有荧光和明场两种成像模式,兼容双倍标准尺寸的大型切片扫描,方便用户观察大体积组织样本,进一步提升科研与药物研发工作的应用价值。
NanoZoomer 是滨松集团(欧盟、日本、英国、美国)的注册商标。
设备除搭载自主研发的高速高灵敏度sCMOS 相机外,我们采用了一种具有滤光片的透射式照明光学系统,可支持六色荧光的扫描。每个通道均可输出图像文件,允许单波长查看或叠加多个波长进行综合分析。
案例 1:多色小鼠胚胎荧光图像
●荧光扫描速度:6 色,20× mode 约 16 min
● 扫描区域:7 mm × 12 mm
● 荧光染料:DAPI / Aqua / Green / Gold / Red / Far Red
● 曝光时间:80 ms / 32 ms / 112 ms / 224 ms / 224 ms / 112 ms
● 增益:8× each
图像 1
扫描过程中,提高增益,可在更短曝光时间内获得高亮度荧光图像。曝光时间可缩短至原始时间的 1/8,实现更短的扫描时间,同时降低荧光淬灭风险。
扫描区域(40× mode):10 mm× 10 mm
滤光片:DAPI / FITC / TRITC
* 扫描时间基于实际测量数据,包含从加载切片到扫描完成的总时长。
图像 2:
图像 2:多色小鼠肾脏荧光图像
● 荧光扫描速度:3 色,40 × mode 约 9 min
● 扫描区域:7 mm × 13 mm(图像为局部视场)
● 荧光染料:DAPI / Alexa 488 / Alexa 568
● 曝光时间:10 ms / 5 ms / 5 ms
焦点偏移功能,可精确调节焦平面,可获得对焦清晰的图像。可解决如盖玻片污染导致类似的失焦问题,省去重新制备样本。
图像 3
* 扫描时间基于15 mm × 15 mm、5 个焦点、明场扫描的测试条件
| 产品名称 | NanoZoomer S60v2 数字切片扫描仪 | |
|---|---|---|
| 产品型号 | C16600-01 | |
| ●扫描速度 *1 | 20× mode | 约 60 s (15 mm × 15 mm) |
| 40× mode | 约 75 s (15 mm × 15 mm) | |
| 物镜 | 20× NA 0.75 | |
| 切片尺寸 *2 | 标准尺寸 | 25.0 mm 至 26.0 mm × 75.0 mm 至 76.0 mm(厚度为 0.9mm 至 1.2mm) |
| 双倍尺寸(选配) | 51.0 mm 至 52.0 mm × 75.0 mm 至 76.0 mm(厚度为 0.9mm 至 1.2mm) | |
| 装载数量 | 标准尺寸 | 最大 60 片(20 片 × 3 盒)*3 |
| 双倍尺寸 | 最大 30 片(10 片 × 3盒)*3 | |
| 扫描分辨率 | 20× mode | 约 0.46 μm/像素 |
| 40× mode | 约 0.23 μm/像素 | |
| 聚焦方式 | 预聚焦 | |
| Z-stack 功能 | 有 | |
| 图像压缩 | 压缩图像(JPEG),未压缩图像(8 bit ) | |
| 可读条形码 | 一维条形码 | Code 39 码 、Code 128 码 、交叉 25 码、Codabar 码、EAN-8 码和 UPC-E 码 |
| 二维条形码 *4 | DataMatrix 码 (ECC200)、QR 码 Ⓡ(QR 码 Model-1、QR 码 Model-2) | |
| 电源 | AC100 V ~ AC240 V | |
| 用电功耗 | 120 VA | |
*1 扫描具有 5 个焦点的 15 mm × 15 mm 正方形区域时。
*2 标准尺寸切片是单切片,双倍标准尺寸切片是双倍宽度的大型切片。
*3 最多可设置 3 个切片盒,支持标准尺寸和双倍标准尺寸切片的组合使用。
*4 读取二维条码需安装选配软件。
矩阵表显示了在每个地区注册为医疗系统的 NanoZoomer IVD 系列。
| 美国 | 欧盟 | 英国 | 瑞士 | 中国 | 加拿大 | 台湾 | 韩国 | 日本 | 土耳其 | 以色列 | 印度 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NanoZoomer S20MD | C16300-21MDEU | C16300-21MDEU | C16300-21MDEU | C16300-31MDCA | C16300-61MDK | C16300-11MDJ | C16300-21MDEU | C16300-71MD | ||||
| NanoZoomer S60v2MD | C16600-21MDEU | C16600-21MDEU | C16600-21MDEU | C16600-21MDEU | C16600-21MDEU | |||||||
| NanoZoomer S360MD | C13220-01MD | C13220-21MDEU | C13220-21MDEU | C13220-21MDEU | C13220-61MDK | C13220-11MDJ | C13220-21MDEU | C13220-21MDEU | C13220-71MD | |||
| NanoZoomer S540MD | C17400-21MDEU | C17400-21MDEU | C17400-21MDEU | C17400-00MD | C17400-21MDEU | C17400-21MDEU | ||||||
| NanoZoomer S60 | C13210-01 | |||||||||||
| NanoZoomer S360 | C13220-01 | C13220-31 | C13220-01 |
重要声明
在美国,C13220-01MD NanoZoomer S360MD 玻片扫描仪系统可用于以下经验证的 FDA 批准显示器,进行初步诊断:
・JVC JD-C240BN01A *显示器经 FDA 批准可与 NanoZoomer S360MD 配合使用。
・BARCO MDPC-8127 *显示器本身已获得 FDA 批准。
在欧洲,以下产品符合体外诊断用途的 IVDR (EU)、UK MDR2002 (UK) 和 IvDO (CH) 标准:
C13220-21MDEU NanoZoomer S360MD 玻片扫描仪系统、C16600-21MDEU NanoZoomer S60v2MD 玻片扫描仪系统、C16300-21MDEU NanoZoomer S20MD 玻片扫描仪系统和 C17400-21MDEU NanoZoomer S540MD 玻片扫描仪系统。
在中国,以下产品已注册用于体外诊断:
C13220-01 NanoZoomer S360 和 C13210-01 NanoZoomer S60。
在加拿大,C13220-31 NanoZoomer S360、C17400-00MD NanoZoomer S540MD 玻片扫描仪系统 和 C16300-31MDCA NanoZoomer S20MD 玻片扫描仪系统具有医疗器械许可证。
在台湾,C13220-01 NanoZoomer S360 已注册为医疗器械。
在韩国,C13220-61MDK NanoZoomer S360MD 和 C16300-61MDK NanoZoomer S20MD 玻片扫描仪系统已注册为体外诊断医疗设备。
在日本,C13220-11MDJ NanoZoomer S360MD 玻片扫描仪系统和 C16300-11MDJ NanoZoomer S20MD 玻片扫描仪系统已获批准为医疗器械。
在土耳其,C13220-21MDEU NanoZoomer S360MD 玻片扫描仪系统、C16600-21MDEU NanoZoomer S60v2MD 玻片扫描仪系统和 C16300-21MDEU NanoZoomer S20MD 玻片扫描仪系统已注册为医疗器械。
在以色列,C13220-21MDEU NanoZoomer S360MD 玻片扫描仪系统和 C16600-21MDEU NanoZoomer S60v2MD 玻片扫描仪系统已注册为医疗器械。
在印度,C13220-71MD NanoZoomer S360MD 玻片扫描仪系统 和 C16300-71MD NanoZoomer S20MD 玻片扫描仪系统具有医疗器械许可证。
在其他国家/地区,NanoZoomer 系列仅供研究使用,不得用于临床诊断目的。
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