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案例研究 | qCMOS®相机
生命科学
Tokai National Higher Education and Research System下属Gifu University的Institute for Glyco-core Research (iGCORE) 之中的Cell Biophysics Laboratory，正在研究解析细胞内及细胞膜表面分子的作用机制。2022年，该实验室引进ORCA-Quest作为单分子荧光观测相机。我们通过采访了解了ORCA-Quest的引入原因、使用体验及其未来研究展望。
在活体细胞与动物的检测和成像中，生物发光报告基因技术被证明是一种具有潜力的方法，在神经科学研究领域尤其如此。
Michael Krieg 博士及其协作团队（来自位于西班牙Castelldefels的Institut de Ciencies Fotòniques (ICFO) ），揭示了生物发光显微技术在观测秀丽隐杆线虫和其他生物学模式生物方面的优势和极限突破，论证了快速细胞动力学的体积成像。
Drew Robson 博士目前在德国 Max Planck Institute for Biological Cybernetics 从事研究工作，他系统地开发了各种方法，使用定量光子数分辨相机观测斑马鱼幼体在自然行为过程中的大脑功能。
为了达到最佳单分子成像性能，Institute of Genetics and Developmental Biology, Chinese Academy of Sciences 的 Dr. Jiachao Xu搭建了 TIRF 显微镜，并在最近几年不断改进。近期，Dr. Xu在其活细胞血管紧张素 II 1 型受体 (AT1R) 单分子荧光成像实验中，对 EM-CCD 与 qCMOS 两种相机的性能进行了比较。
天文学
The University of Electro-Communications 下属 Department of Communication Engineering and Informatics 的 Hosokawa Laboratory 使用高灵敏度相机观测极光。极光观测需要高帧率来观测形态和动态，需要高灵敏度来检测暗极光，需要低噪声来流畅地分析获取的图像，并且需要大尺寸传感器来实现宽场成像。ORCA-Quest qCMOS® 相机解决了这些问题。
高能物理同步辐射
Tohoku University 下属 International Center for Synchrotron Radiation Innovation Smart (SRIS) 借助下一代同步辐射设施“NanoTerasu”开发前沿成像技术。“Spatio-Temporal Imaging Smart Lab”中心安装的 X 射线成像系统采用我们的 ORCA-Quest 2 qCMOS® 相机作为探测器。 Spatio-Temporal Imaging Smart Lab 的成员 Wataru Yashiro 博士已将 ORCA-Quest 2 qCMOS 相机集成到 NanoTerasu 光束线中，以开展各类实验。我们采访了 Yashiro 博士，以深入了解其研究、利用 ORCA-Quest 2 所取得的成就以及未来研究展望。
Japan Synchrotron Radiation Research Institute (JASRI) 为 SPring-8 大型同步辐射设施的运行、维护和利用提供技术支持。该机构还支持使用 SACLA 和 NanoTerasu。其中，Microscopic and Dynamic Imaging Team, Scattering and Imaging Division 负责开发利用同步辐射的 X 射线成像系统，并为想要获取 X 射线显微图像的研究人员提供技术支持。ORCA®-Quest qCMOS® 相机被用作该 X 射线显微成像系统的探测器。
National Institute of Advanced Industrial Science and Technology (AIST) 下属 National Metrology Institute of Japan (NMIJ) 的 Research Institute for Measurement and Analytical Instrumentation 之中的 Advanced Beam Measurement Group，正在致力于开发用于先进重离子放射治疗的 α 射线成像技术。这项研究使用 ORCA®-Quest qCMOS® 相机作为探测器。
光谱学
qCMOS 相机具有极低的暗噪声等优异特性，弱信号检出能力出色。本实验结合使用 qCMOS 相机与光栅光谱仪，并开发了新的软件同时控制这两种装置，用于检测针尖增强拉曼散射 (TERS)。为此，该团队测试了 qCMOS 相机对于拉曼或弱信号拉曼的检测能力，并探索了其他应用可能性。
在拉曼成像中，缩短测量时间是一个非常重要的因素。要实现这一点，需要在短时间内检测拉曼信号，这就要求相机具有高灵敏度和低噪声，以及多像素和高速度。我们测量了我们的光子数分辨相机（qCMOS 相机）的信噪比和光谱动态范围，并与 EM-CCD 相机进行比较，结果表明了 qCMOS 相机的优越性。
材料科学
相机应用案例研究集
同步辐射分析“Ryugu”相机应用案例研究
人们认为，小行星Ryugu仍含有约46亿年前的水和有机化合物，我们的太阳系被认为是在那时形成的。我们采访了负责分析Ryugu样品的Japan Synchrotron Radiation Research Institute (JASRI) 的 Mr. Uesugi，了解分析方法和结果以及未来前景。
本案例研究包括对 Mr. Uesugi的采访，并介绍了我们适用于同步辐射成像的相机产品阵容。
天文相机应用案例研究
天文学是一个进行研究以发现和探索未知天体和天文现象的领域。本手册介绍了此类用途的示例，并识别适用于每种用途的相机。
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